Description
What Sutent is?
SUTENT is a kinase inhibitor indicated for the treatment of:
• Gastrointestinal stromal tumor (GIST) after disease progression on or intolerance to imatinib mesylate.
• Advanced renal cell carcinoma (RCC).
• Progressive, well-differentiated pancreatic neuroendocrine tumors (pNET) in patients with unresectable locally advanced or metastatic disease.
What Sunitinib is?
Sunitinib (marketed as Sutent by Pfizer, and previously known as SU11248) is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor that was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) on January 26, 2006. Sunitinib was the first cancer drug simultaneously approved for two different indications.