Description
What Hamsyl is?
Pegaspargase Indicated for the treatment of:
- Acute Lymphoblastic Leukemia: With the combination of prednisone, anthracycline, and vincristine for the first-line treatment of patients with Acute Lymphoblastic Leukemia.
- Acute Lymphoblastic Leukemia and Hypersensitivity to Asparaginase: Patients with Acute Lymphoblastic Leukemia (ALL) and hypersensitivity to native forms of L-Asparaginase.
What Pegaspargase is?
Pegaspargase, sold under the trade name Oncaspar, is a medication used in the treatment of acute lymphoblastic leukemia (ALL). Often it is used together with anthracycline, vincristine, and prednisone. It is used by injection.
Common side effects include allergic reactions, blood clotting problems, high blood sugar, liver problems, pancreas inflammation, and blood clots in the brain. Its use during pregnancy may harm the baby. It is a modified version of the enzyme asparaginase which has undergone PEGylation. It works by breaking down asparagine, decreasing its availability to make protein.
