Generic Name(s): cabazitaxel
Cabazitaxel is the generic name for the trade name drug Jevtana®. In some cases, health care professionals may use the trade name Jevtana® when referring to the generic drug name cabazitaxel.

Drug Type:
Jevtana is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This medication is classified as a "taxane derivitive" and an "anti-microtubule agent." (For more detail, see "How Jevtana Works" below)

What Jevtana Is Used For:
Jevtana is approved for treatment [in combination with prednisone] for treatment of patients with castrate resistant metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen.

Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.

How Jevtana Is Given:
  • Jevtana is given through a vein (intravenously, IV)
  • There is no pill form of Jevtana.
  • You will take an corticosteroid pill, prednisone, twice a day, every day while being treated with Jevtana.
  • You will be given pre-medications about 30 minutes prior to each Jevtana infusion. This is to decrease the risk of having a reaction to the Jevtana.

The amount of Jevtana that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition you have. Your doctor will determine your exact dosage and schedule.

Jevtana Side effects:
Important things to remember about the side effects of Jevtana:
  • Most people will not experience all of the Jevtana side effects listed.
  • Jevtana side effects are often predictable in terms of their onset, duration, and severity.
  • Jevtana side effects are often reversible and are likely to improve after therapy is complete.
  • Jevtana side effects may be quite manageable. There are many options to minimize or prevent the side effects of cabazitaxel.
  • There is no relationship between the presence or severity of side effects and the efficacy of the medication

The following side effects are common (occurring in greater than 30%) for patients taking Jevtana:
  • Low blood counts: Your white and red blood cells and platelets may temporarily decrease. This can put you at increased risk for infection, anemia and/or bleeding.
  • Nadir: this is the 'low point'. It is the point at which your blood counts are the lowest they will be during this treatment.
    Nadir: 8-12 day
  • Diarrhea
  • Fatigue
  • Nausea